Publications

Small Molecule Targeting of Oxysterol-Binding Protein (OSBP)-Related Protein 4 and OSBP Inhibits Ovarian Cancer Cell Proliferation in Monolayer and Spheroid Cell Models

Ryan C. Bensen, Gokhan Gunay, Matthew C. Finneran, Isha Jhingan, Handan Acar*, and Anthony W. G. Burgett

ACS Pharmacology and Translation Science, 2021, published online 

Single Cell Mass Spectrometry Quantification of Anticancer Drugs: Proof of Concept in Cancer Patients

Ryan C. Bensen, Shawna J. Standke, Devon H. Colby, Naga Rama Kothapalli, Anh T. Le-McClain, Michael A. Patten, Abhishek Tripathi, Jonathan E. Heinlen, Zhibo Yang, and Anthony W. G. Burgett

ACS Pharmacology and Translation Science, 2021, 4(1): 96-100.

Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site

Simon S. Terzyan, Anthony W. G. Burgett, Annie Heroux, Clyde A. Smith, Blaine H. M. Mooers, Marie H. Hanigan

Journal of Biological Chemistry, 2021, 296: 100066.

Indole C6 Functionalization of Tryprostatin B Using Prenyltransferase CdpNPT

Eric D. Gardner, Dustin A. Dumas, Matthew C. Finneran, Sara M. Brown, Anthony W. G. Burgett, Shanteri Singh

Catalysts, 2020, 10(11) 1247.

FgaPT2, a biocatalytic tool for alkyl-diversification of indole
natural products

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Integrated Cell Manipulation Platform Coupled with Single-probe Mass Spectrometry for the Analysis of Single Suspension Cells.

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Mass Spectrometry Measurement of Single Suspended Cells using Combined Cell Manipulation System and the Single-probe Device.

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Transient Compound Treatment Induces a Multigenerational Reduction of Oxysterol-Binding Protein (OSBP) Levels and Prophylactic Antiviral Activity.

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Quantification of Drug Molecules in Live Single Cells using the Single-probe Mass Spectrometry Technique

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Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes.

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Human γ-Glutamyl Transpeptidase 1 STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS

Simon S. Terzyan, Anthony W. G. Burgett, Annie Heroux, Clyde A. Smith, Blaine H. M. Mooers, Marie H. Hanigan

Journal of Biological Chemistry 2015, 290(28): 17576

Quantification of Gold Nanoparticle Uptake into Cancer Cells using Single Cell ICP-MS.

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The Single-probe: A Miniaturized Multifunctional Device for Single Cell Mass Spectrometry Analysis.

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Natural Products Reveal Cancer Cell Dependence on Oxysterol-Binding Proteins.

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Therapeutic Anticancer Efficacy of a Synthetic Diazonamide Analog in the Absence of Overt Toxicity.

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Diazonamide Toxins Reveal an Unexpected Function for Ornithine g-Amino Transferase in Mitotic Cell Division.

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A Concise and Flexible Total Synthesis of Diazonamide A.

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Total Synthesis of Nominal Diazonamides—Part 2: On the True Structure and Origin of Natural Isolates.

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Synthetic seco Forms of (-)-Diazonamide A.

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